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Imbalanced classification is an important task in supervised learning, and Synthetic Minority Over-sampling Technique (SMOTE) is the most common method to address it. However, the performance of SMOTE deteriorates in the presence of label noise. Current generalizations of SMOTE try to tackle this problem by either selecting some samples in minority class as seed samples or combining SMOTE with a certain noise filter. Unfortunately, the former approach usually introduces extra parameters difficult to be optimized, and the latter one relies heavily on the performance of certain specific noise filter. In this paper, a self-adaptive robust SMOTE, called RSMOTE, is proposed for imbalanced classification with label noise. In RSMOTE, relative density has been introduced to measure the local density of every minority sample, and the non-noisy minority samples are divided into the borderline samples and safe …