作者
Lauren AM Lebois, Nathaniel G Harnett, Sanne JH van Rooij, Timothy D Ely, Tanja Jovanovic, Steven E Bruce, Stacey L House, Caitlin Ravichandran, Nathalie M Dumornay, Katherine E Finegold, Sarah B Hill, Julia B Merker, Karlye A Phillips, Francesca L Beaudoin, Xinming An, Thomas C Neylan, Gari D Clifford, Sarah D Linnstaedt, Laura T Germine, Scott L Rauch, John P Haran, Alan B Storrow, Christopher Lewandowski, Paul I Musey Jr, Phyllis L Hendry, Sophia Sheikh, Christopher W Jones, Brittany E Punches, Robert A Swor, Meghan E McGrath, Lauren A Hudak, Jose L Pascual, Mark J Seamon, Elizabeth M Datner, Anna M Chang, Claire Pearson, Robert M Domeier, Niels K Rathlev, Brian J O’Neil, Paulina Sergot, Leon D Sanchez, Mark W Miller, Robert H Pietrzak, Jutta Joormann, Deanna M Barch, Diego A Pizzagalli, John F Sheridan, Jordan W Smoller, Beatriz Luna, Steven E Harte, James M Elliott, Ronald C Kessler, Karestan C Koenen, Samuel A McLean, Jennifer S Stevens, Kerry J Ressler
发表日期
2022/9/1
期刊
American journal of psychiatry
卷号
179
期号
9
页码范围
661-672
出版商
American Psychiatric Association
简介
Objective
Dissociation, a disruption or discontinuity in psychological functioning, is often linked with worse psychiatric symptoms; however, the prognostic value of dissociation after trauma is inconsistent. Determining whether trauma-related dissociation is uniquely predictive of later outcomes would enable early identification of at-risk trauma populations. The authors conducted the largest prospective longitudinal biomarker study of persistent dissociation to date to determine its predictive capacity for adverse psychiatric outcomes following acute trauma.
Methods
All data were part of the Freeze 2 data release from the Advancing Understanding of Recovery After Trauma (AURORA) study. Study participants provided self-report data about persistent derealization (N=1,464), a severe type of dissociation, and completed a functional MRI emotion reactivity task and resting-state scan 2 weeks posttrauma (N=145). Three …
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LAM Lebois, NG Harnett, SJH van Rooij, TD Ely… - American journal of psychiatry, 2022