作者
Vitória Piai, Elke De Witte, Joanna Sierpowska, Xiaochen Zheng, Leighton B Hinkley, Danielle Mizuiri, Robert T Knight, Mitchel S Berger, Srikantan S Nagarajan
发表日期
2020/8/1
期刊
Journal of Cognitive Neuroscience
卷号
32
期号
8
页码范围
1497-1507
出版商
MIT Press
简介
Little is known about language impairment in brain tumor patients, especially in the presurgical phase. Impairment in this population may be missed because standardized tests fail to capture mild deficits. Additionally, neuroplasticity may also contribute to minimizing language impairments. We examined 14 presurgical patients with brain tumors in the language-dominant hemisphere using magnetoencephalography (MEG) while they performed a demanding picture–word interference task, that is, participants name pictures while ignoring distractor words. Brain tumor patients had behavioral picture-naming effects typically observed in healthy controls. The MEG responses also showed the expected pattern in its timing and amplitude modulation typical of controls, but with an altered spatial distribution of right hemisphere sources, in contrast to the classic left hemisphere source found in healthy individuals. This …
引用总数
2020202120222023202424343
学术搜索中的文章
V Piai, E De Witte, J Sierpowska, X Zheng, LB Hinkley… - Journal of Cognitive Neuroscience, 2020