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Mobile edge computing (MEC) is being introduced and leveraged in many domains, but few studies have addressed MEC for secure in-home therapy management. To this end, this paper presents an in-home therapy management framework, which leverages the IoT nodes and the blockchain-based decentralized MEC paradigm to support low-latency, secure, anonymous, and always-available spatiotemporal multimedia therapeutic data communication within an on-demand data-sharing scenario. To the best of our knowledge, this non-invasive, MEC-based IoT therapy platform is first done by our group. This platform can provide a full-body joint range of motion data for physically challenged individuals in a decentralized manner. With MEC, the framework can provide therapy diagnostic and analytical data on demand to a large portion of humanity who are either born with disabilities or became disabled due to …