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The immediate availability of blood can save other lives in case of emergency needs. Blood transfusion is a continuous demand, as it is widely required for many medical surgeries and critical operations. Therefore, there is a need to manage the whole process of supplying blood from blood donors to the hospitals and transfusion centers as well as matching the blood compatibility between the donors and patients. This comparative study reviews the existing approaches for blood donation and blood assignment management systems which aim to provide a continuous supply of blood products to transfusion centers and hospitals by optimizing the process of blood donations and predicting the future behavior of blood donation. The optimization process of blood donations is based on minimizing the wastage of blood units with regards to expiration. It also aims to reduce the additional importation of blood units from …