作者
Giulia Giacomucci, Salvatore Mazzeo, Sonia Padiglioni, Silvia Bagnoli, Laura Belloni, Camilla Ferrari, Laura Bracco, Benedetta Nacmias, Sandro Sorbi, Valentina Bessi
发表日期
2022/4/1
期刊
Neurological Sciences
页码范围
1-10
出版商
Springer International Publishing
简介
Background
Subjective Cognitive Decline (SCD) is a self-experienced decline in cognitive capacity with normal performance on standardized cognitive tests, showing to increase risk of Alzheimer’s Disease (AD). Cognitive reserve seems to influence the progression from SCD to Mild Cognitive Impairment (MCI) and to AD. The aim of our study was to investigate gender differences in cognitive reserve evaluating how sex might modulate the role of cognitive reserve on SCD.
Methods
We included 381 SCD patients who underwent clinical evaluation, neuropsychological assessment, evaluation of premorbid intelligence by the Test di Intelligenza Breve (TIB), cognitive complaints by the Memory Assessment Clinics Questionnaire (MAC-Q), and apolipoprotein E (APOE) genotyping.
Results
The proportion between women and men was …
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G Giacomucci, S Mazzeo, S Padiglioni, S Bagnoli… - Neurological Sciences, 2022