作者
Tenzin Tsundue, Tenzin Namdon, Tenzin Tsewang, Sonam Topgyal, Tashi Dolma, Dekyi Lhadon, Tsering Choetso, Tenzin Woesal, Tenzin Yangkyi, Amita Gupta, David Peters, Zorba Paster, Dawa Phunkyi, Tsetan Dorji Sadutshang, Richard E Chaisson, Kunchok Dorjee
发表日期
2022/5/1
期刊
BMJ Global Health
卷号
7
期号
5
页码范围
e008271
出版商
BMJ Specialist Journals
简介
Objectives
This study aimed to determine the effectiveness of Covishield vaccine among residents of congregate residential facilities.
Design
A prospective cohort study in congregate residential facilities.
Setting
Dharamshala, Himachal Pradesh, India, from December 2020 to July 2021.
Participants
Residents of all ages in seven facilities—three monasteries, two old age homes and two learning centres—were enrolled.
Exposures
First and second doses of Covishield vaccine against SARS-CoV-2 infection.
Main outcomes measures
Primary outcome was development of COVID-19. Secondary outcome was unfavourable outcomes, defined as a composite of shortness of breath, hospitalisation or death. Vaccine effectiveness (%) was calculated as (1−HR)×100.
Results
There were 1114 residents (median age 31 years) participating in the study, 82% males. Twenty-eight per cent (n=308/1114) were unvaccinated, 50% (n …
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