作者
Marvin M Doyley, Paul M Meaney, Jeffrey C Bamber
发表日期
2000/6/1
期刊
Physics in Medicine & Biology
卷号
45
期号
6
页码范围
1521
出版商
IOP Publishing
简介
This paper describes an inverse reconstruction technique based on a modified Newton Raphson iterative scheme and the finite element method, which has been developed for computing the spatial distribution of Young's modulus from within soft tissues. Computer simulations were conducted to determine the relative merits of reconstructing tissue elasticity using knowledge of (a) known displacement boundary conditions (DBC), and (b) known stress boundary conditions (SBC). The results demonstrated that computing Young's modulus using knowledge of SBC allows accurate quantification of Young's modulus. However, the quality of the images produced using this reconstruction approach was dependent on the Young's modulus distribution assumed at the start of the reconstruction procedure. Computing Young's modulus from known DBC provided relative estimates of tissue elasticity which, despite the …
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