作者
Maryam Pakfetrat, Mohammad Hossein Nikoo, Leila Malekmakan, Mahmood Tabandeh, Jamshid Roozbeh, Mahshid Hashemi Nasab, Mohammad Ali Ostovan, Soheila Salari, Mohammad Kafi, Najmeh Moin Vaziri, Farzad Adl, Mehdi Hosseini, Parviz Khajehdehi
发表日期
2009/9
期刊
International urology and nephrology
卷号
41
页码范围
629-634
出版商
Springer Netherlands
简介
Background
Contrast-induced nephropathy (CIN) is commonly encountered. Because the therapy of choice for prevention of CIN is controversial, in this study we compared the preventive efficacy of bicarbonate (Bi) infusion in dextrose water versus normal saline (NLS) infusion alone or in combination with oral acetazolamide (AZ).
Methods
In a double-blind and randomized clinical trial, all patients undergoing coronary angiography or percutaneous coronary intervention received NLS (NLS group), its combination with AZ (AZ group) or infusion of Bi (Bi group) before the procedures. RIFLE (risk of renal failure, injury to the kidney, failure of kidney function, loss of kidney function, and end-stage renal disease) criteria were used to define CIN-associated acute kidney injury (AKI).
Results
The risk of AKI in CIN was …
学术搜索中的文章
M Pakfetrat, MH Nikoo, L Malekmakan, M Tabandeh… - International urology and nephrology, 2009