作者
Phillip Bokiniec, Niccolò Zampieri, Gary R Lewin, James FA Poulet
发表日期
2018/10/1
来源
Current opinion in neurobiology
卷号
52
页码范围
98-106
出版商
Elsevier Current Trends
简介
Highlights
- Innocuous thermal information is a key component of haptic exploration.
- Thermal perception is immediate and robust from mouse to man.
- Mouse thermosensory system is genetically and optically accessible.
- Circuits and coding principles of thermal processing are starting to be elucidated.
Thermal information about skin surface temperature is a key sense for the perception of object identity and valence. The identification of ion channels involved in the transduction of thermal changes has provided a genetic access point to the thermal system. However, from sensory specific ‘labeled-lines’ to multimodal interactive pathways, the functional organization and identity of the neural circuits mediating innocuous thermal perception have been debated for over 100 years. Here we highlight points in the system that require further attention and review recent advances using in vivo electrophysiology, cellular resolution …
学术搜索中的文章
P Bokiniec, N Zampieri, GR Lewin, JFA Poulet - Current opinion in neurobiology, 2018