作者
Dena van den Bergh, Angeliki P Messina, Debra A Goff, Andriette van Jaarsveld, Renier Coetzee, Yolande de Wet, Elmien Bronkhorst, Adrian Brink, Marc Mendelson, Guy A Richards, Charles Feldman, Natalie Schellack, Community-acquired Pneumonia Study Alliance
发表日期
2020/12/1
期刊
International Journal of Antimicrobial Agents
卷号
56
期号
6
页码范围
106189
出版商
Elsevier
简介
Introduction
: Pharmacists in low-middle-income countries (LMIC) lack in number and antibiotic stewardship (AS) training. We assessed the ability of non-specialised pharmacists to implement stewardship interventions and improve adherence to the South African (SA) community-acquired pneumonia (CAP) guideline in public and private hospitals.
Methods
: This was a multicentre, prospective cohort study of adult CAP patients hospitalised between July 2017 and July 2018. We developed a CAP bundle of seven process measures (diagnostic and AS) that pharmacists used to audit compliance and provide feedback. CAP bundle compliance rates and change in outcome measures [mortality, length of stay (LOS) and infection-related (IR)-LOS] during pre- and post-implementation periods were compared.
Results
: In total 2464 patients in 39 hospitals were included in the final analysis. Post implementation, overall CAP …
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D van den Bergh, AP Messina, DA Goff… - International Journal of Antimicrobial Agents, 2020