作者
Michael I Brener, Nadira B Hamid, Justin A Fried, Amirali Masoumi, Manreet K Kanwar, Mohit Pahuja, Giulio M Mondellini, Lorenzo Braghieri, David T Majure, Paolo C Colombo, Melana Yuzefpolskaya, Gabriel T Sayer, Nir Uriel, Daniel Burkhoff
发表日期
2021/9
期刊
Journal of Cardiac Failure
卷号
27
期号
9
页码范围
991-100
出版商
Churchill Livingstone
简介
Background
Interventricular interaction, which refers to the impact of left ventricular (LV) function on right ventricular (RV) function and vice versa, has been implicated in the pathogenesis of RV failure in LV assist device (LVAD) recipients. We sought to understand more about interventricular interaction by quantifying changes in the RV systolic and diastolic function with varying LVAD speeds.
Methods and Results
Four patients (ages 22–69 years, 75% male, and 25% with ischemic cardiomyopathy) underwent a protocolized hemodynamic ramp test within 12 months of LVAD implantation where RV pressure–volume loops were recorded with a conductance catheter. The end-systolic PV relationship and end-diastolic PV relationship were compared using the V20 and V10 indices (volumes at which end-systolic PV relationship and end-diastolic PV relationship reach a pressure of 20 and 10 mm Hg, respectively). The …
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MI Brener, NB Hamid, JA Fried, A Masoumi… - Journal of Cardiac Failure, 2021