作者
Larry E Roberts, Daniel J Bosnyak, Ian C Bruce, Phillip E Gander, Brandon T Paul
发表日期
2015/9/1
期刊
Hearing research
卷号
327
页码范围
9-27
出版商
Elsevier
简介
It has been proposed that tinnitus is generated by aberrant neural activity that develops among neurons in tonotopic of regions of primary auditory cortex (A1) affected by hearing loss, which is also the frequency region where tinnitus percepts localize (Eggermont and Roberts, 2004, Roberts et al., 2010, Roberts et al., 2013). These models suggest (1) that differences between tinnitus and control groups of similar age and audiometric function should depend on whether A1 is probed in tinnitus frequency region (TFR) or below it, and (2) that brain responses evoked from A1 should track changes in the tinnitus percept when residual inhibition (RI) is induced by forward masking. We tested these predictions by measuring (128-channel EEG) the sound-evoked 40-Hz auditory steady-state response (ASSR) known to localize tonotopically to neural sources in A1. For comparison the N1 transient response localizing to …
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