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The popularity of smartphones and smartphone applications means that data is the dominant traffic type in current mobile networks. In this paper we present our work on a systematic investigation into facets of the LTE/EPC architecture that impact the performance of TCP as the predominant transport layer protocol used by applications on mobile networks. We found that (1) load increase in a cell causes dramatic bandwidth reduction on UEs and significantly degrades TCP performance, (2) seamless handover causes significant TCP losses while lossless handover increases TCP segments' delay.