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Sensors and smartphones are used in industry and healthcare technology for data gathering. The sensed data can be acquired by devices and processed through multiple gateways to the Internet of things (IoT) enabled cloud framework. Device-to-device (D2D) communication paradigm is a central part of the third generation partnership project standards to facilitate peer-to-peer connectivity that will be an important part of IoT. There is no centralized control in D2D which strengthens the wireless networks more energy-efficient and spectrum. The D2D enhances the data transmission process with advance security schemes and also improves the quality of service. This paper surveyed recent works on D2D, which is mainly focused on resource allocation, power consumption, security, and also highlights the major challenges. The role of D2D communication systems in healthcare has been discussed here.