作者
Hilary Whitworth, Sarah E Sartain, Riten Kumar, Katherine Armstrong, Lance Ballester, Marisol Betensky, Clay T Cohen, Rosa Diaz, Caroline Diorio, Neil A Goldenberg, Julie Jaffray, Jacquelyn Keegan, Kendra Malone, Adrienne G Randolph, Stacey Rifkin-Zenenberg, Wendy Seto Leung, Anthony Sochet, Lakshmi Srivaths, Ayesha Zia, Leslie Raffini
发表日期
2021/7/15
期刊
Blood, The Journal of the American Society of Hematology
卷号
138
期号
2
页码范围
190-198
出版商
American Society of Hematology
简介
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with thrombotic complications in adults, but the incidence of COVID-19-related thrombosis in children and adolescents is unclear. Most children with acute COVID-19 have mild disease, but coagulopathy has been associated with multisystem inflammatory syndrome in children (MIS-C), a postinfectious complication. We conducted a multicenter retrospective cohort study to determine the incidence of thrombosis in children hospitalized with COVID-19 or MIS-C and evaluate associated risk factors. We classified patients into 1 of 3 groups for analysis: COVID-19, MIS-C, or asymptomatic SARS-CoV-2. Among a total of 853 admissions (COVID-19, n = 426; MIS-C, n = 138; and asymptomatic SARS-CoV-2, n = 289) in 814 patients, there were 20 patients with thrombotic events (TEs …
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H Whitworth, SE Sartain, R Kumar, K Armstrong… - Blood, The Journal of the American Society of …, 2021