作者
Michelle C Odden, Mark J Pletcher, Pamela G Coxson, Divya Thekkethala, David Guzman, David Heller, Lee Goldman, Kirsten Bibbins-Domingo
发表日期
2015/4/21
期刊
Annals of internal medicine
卷号
162
期号
8
页码范围
533-541
出版商
American College of Physicians
简介
Background
Evidence to guide primary prevention in adults aged 75 years or older is limited.
Objective
To project the population impact and cost-effectiveness of statin therapy in adults aged 75 years or older.
Design
Forecasting study using the Cardiovascular Disease Policy Model, a Markov model.
Data Sources
Trial, cohort, and nationally representative data sources.
Target Population
U.S. adults aged 75 to 94 years.
Time Horizon
10 years.
Perspective
Health care system.
Intervention
Statins for primary prevention based on low-density lipoprotein cholesterol threshold of 4.91 mmol/L (190 mg/dL), 4.14 mmol/L (160 mg/dL), or 3.36 mmol/L (130 mg/dL); presence of diabetes; or 10 …
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