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This paper studies the coexistence of heterogeneous multi-hop networks, which use different physical-layer technologies. We propose a new paradigm, called cooperative interference mitigation (CIM), which exploits recent advancement in interference cancellation (IC), such as technology-independent multiple output. CIM makes it possible for disparate networks to cooperatively mitigate the interference to/from each other to enhance everyone's performance. We first show the feasibility of CIM among heterogeneous multi-hop networks by exploiting only channel-ratio information. Then, we establish two tractable models to characterize the CIM behaviors of both networks by using full IC and receiver-side IC only. We propose two bi-criteria optimization problems aiming at maximizing both networks' throughput, while cooperatively canceling the interference between them based on our two models. Several …