作者
Yu Tien Wang, Sahar D Mohammed, Adam D Farmer, Duolao Wang, Natalia Zarate, Anthony R Hobson, Per M Hellström, John R Semler, Braden Kuo, Satish S Rao, William L Hasler, Michael Camilleri, S Mark Scott
发表日期
2015/9
期刊
Alimentary pharmacology & therapeutics
卷号
42
期号
6
页码范围
761-772
简介
Background
The wireless motility capsule (WMC) offers the ability to investigate luminal gastrointestinal (GI) physiology in a minimally invasive manner.
Aim
To investigate the effect of testing protocol, gender, age and study country on regional GI transit times and associated pH values using the WMC.
Methods
Regional GI transit times and pH values were determined in 215 healthy volunteers from USA and Sweden studied using the WMC over a 6.5‐year period. The effects of test protocol, gender, age and study country were examined.
Results
For GI transit times, testing protocol was associated with differences in gastric emptying time (GET; shorter with protocol 2 (motility capsule ingested immediately after meal) vs. protocol 1 (motility capsule immediately before): median difference: 52 min, P = 0.0063) and colonic transit time (CTT; longer with protocol 2: median 140 min, P = 0.0189), but had no overall effect …
学术搜索中的文章
YT Wang, SD Mohammed, AD Farmer, D Wang… - Alimentary pharmacology & therapeutics, 2015