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A model for a spiral-wound reverse osmosis system using the three-parameter membrane transport model by Spiegler-Kedem is presented. The pressure drops in the permeate channel, feed channel and also the variation of the mass transfer coefficient along the feed channel were taken into account. An analytical solution was not possible due to the large number of nonlinear model equations; therefore, a computer solution utilizing finite differences was employed. The data generated by the simulation of the proposed model clearly indicate that neglecting the variation in the mass transfer coefficient and pressure drop along the flow channels can lead to errors in permeate concentration, though the effect on permeate flow rate may not be significant. The significance of the reflection coefficient in the membrane transport model was also investigated. A method for estimation of the model parameters is also presented …