作者
Maozhong Li, Jing Li, Lu Kang, Cheng Gong, Ming Luo, Xue Wang, Xuejiao Guan, Yigang Tong, Fang Huang
发表日期
2023/12
期刊
Journal of Medical Virology
卷号
95
期号
12
页码范围
e29284
简介
To investigate the molecular epidemiological characteristics and genetic variations of human adenovirus (HAdV) in acute respiratory tract infections in Beijing. Whole‐genome sequencing and phylogenetic analyses were performed for 83 strains of HAdV with different types in Beijing from 2014 to 2019. The clinical characteristics of HAdV infection were analyzed statistically. HAdV‐B was divided into four genotypes, including B3 (n = 11), B7 (n = 13), B14 (n = 4), and B55 (n = 2). HAdV‐C was divided into three genotypes, including C1 (n = 14), C2 (n = 13), and C5 (n = 10). In HAdV‐C, nine recombinant adenovirus strains were identified in type 1, and seven recombinant strains were found in type 2. In type 1, we found three newly emerged intraspecific recombinant strains (A47, A48, and A52) collected in 2017, 2018, and 2019, respectively. In addition, the previously reported recombinant strains of …
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M Li, J Li, L Kang, C Gong, M Luo, X Wang, X Guan… - Journal of Medical Virology, 2023