作者
Anna A Pimenova, Edoardo Marcora, Alison M Goate
发表日期
2017/9/19
期刊
Immunity
卷号
47
期号
3
页码范围
398-400
出版商
Elsevier
简介
Microglial cell function is implicated in the etiology of Alzheimer's disease by human genetics. In this issue of Immunity, Krasemann et al. (2017) describe a gene expression signature associated with an APOE- and TREM2-dependent response of microglia to brain tissue damage that accumulates in aging and disease, defining an axis that might be amenable to therapeutic targeting.
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