作者
Ali Abbara, Maya Al-Memar, Maria Phylactou, Elisabeth Daniels, Bijal Patel, Pei C Eng, Rans Nadir, Chioma Izzi-Engbeaya, Sophie A Clarke, Edouard G Mills, Tia Hunjan, Ewa Pacuszka, Lisa Yang, Paul Bech, Tricia Tan, Alexander N Comninos, Tom W Kelsey, Christopher Kyriacou, Hanine Fourie, Tom Bourne, Waljit S Dhillo
发表日期
2022/1/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
107
期号
1
页码范围
e71-e83
出版商
Oxford University Press
简介
Context
Antenatal complications such as hypertensive disorders of pregnancy (HDP), fetal growth restriction (FGR), gestational diabetes (GDM), and preterm birth (PTB) are associated with placental dysfunction. Kisspeptin has emerged as a putative marker of placental function, but limited data exist describing circulating kisspeptin levels across all 3 trimesters in women with antenatal complications.
Objective
We aimed to assess whether kisspeptin levels are altered in women with antenatal complications.
Methods
Women with antenatal complications (n = 105) and those with uncomplicated pregnancies (n = 265) underwent serial ultrasound scans and blood sampling at the Early Pregnancy Assessment Unit at Hammersmith Hospital, UK, at least once during each trimester (March 2014 to March 2017). The women with antenatal complications (HDP …
学术搜索中的文章
Changes in circulating kisspeptin levels during each trimester in women with antenatal complications
A Abbara, M Al-Memar, M Phylactou, E Daniels, B Patel… - The Journal of Clinical Endocrinology & Metabolism, 2022