作者
Felix Mahfoud, Christian Ukena, Roland E Schmieder, Bodo Cremers, Lars C Rump, Oliver Vonend, Joachim Weil, Martin Schmidt, Uta C Hoppe, Thomas Zeller, Axel Bauer, Christian Ott, Erwin Blessing, Paul A Sobotka, Henry Krum, Markus Schlaich, Murray Esler, Michael Böhm
发表日期
2013/7/9
期刊
Circulation
卷号
128
期号
2
页码范围
132-140
出版商
Lippincott Williams & Wilkins
简介
Background
Catheter-based renal sympathetic denervation (RDN) reduces office blood pressure (BP) in patients with resistant hypertension according to office BP. Less is known about the effect of RDN on 24-hour BP measured by ambulatory BP monitoring and correlates of response in individuals with true or pseudoresistant hypertension.
Methods and Results
A total of 346 uncontrolled hypertensive patients, separated according to daytime ambulatory BP monitoring into 303 with true resistant (office systolic BP [SBP] 172.2±22 mm Hg; 24-hour SBP 154±16.2 mm Hg) and 43 with pseudoresistant hypertension (office SBP 161.2±20.3 mm Hg; 24-hour SBP 121.1±19.6 mm Hg), from 10 centers were studied. At 3, 6, and 12 months follow-up, office SBP was reduced by 21.5/23.7/27.3 mm Hg, office diastolic BP by 8.9/9.5/11.7 mm Hg, and pulse pressure by 13.4/14.2/14.9 mm Hg (n=245/236/90; P for all <0.001 …
学术搜索中的文章
F Mahfoud, C Ukena, RE Schmieder, B Cremers… - Circulation, 2013