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A surface impedance sensor and method are provided. The surface impedance sensor generally includes first and second electrodes, a driver circuit to drive the electrodes at a plurality of driving frequencies, and a detection circuit to measure the impedance across the first and second electrodes for comparison against a plurality of reference profiles. The method generally includes measuring the localized surface impedance for each of a plurality of driving frequencies to generate a measured profile, and correlating the measured profile with a reference profile. The system and method can verify contact with a particular surface and can be used with a variety of host devices, including for example ultrasound delivery devices.