作者
Yasser Sakr, Suzana M Lobo, Rui P Moreno, Herwig Gerlach, V Marco Ranieri, Argyris Michalopoulos, Jean-Louis Vincent, SOAP Investigators jlvincen@ ulb. ac. be
发表日期
2012/12
期刊
Critical care
卷号
16
页码范围
1-9
出版商
BioMed Central
简介
Introduction
Recognition of patterns of organ failure may be useful in characterizing the clinical course of critically ill patients. We investigated the patterns of early changes in organ dysfunction/failure in intensive care unit (ICU) patients and their relation to outcome.
Methods
Using the database from a large prospective European study, we studied 2,933 patients who had stayed more than 48 hours in the ICU and described patterns of organ failure and their relation to outcome. Patients were divided into three groups: patients without sepsis, patients in whom sepsis was diagnosed within the first 48 hours after ICU admission, and patients in whom sepsis developed more than 48 hours after admission. Organ dysfunction was assessed by using the sequential organ failure assessment (SOFA) score.
Results
A total of 2,110 …
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Y Sakr, SM Lobo, RP Moreno, H Gerlach, VM Ranieri… - Critical care, 2012