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DL has achieved great success in signal processing and communications and has become a promising technology for future wireless communications. Existing works mainly focus on exploiting DL to improve the performance of communication systems. However, the high memory requirement and computational complexity constitute a major hurdle for the practical deployment of DL-based communications. In this article, we investigate how to compress and accelerate the neural networks (NNs) in communication systems. After introducing the deployment challenges for DL-based communication algorithms, we discuss some representative NN compression and acceleration techniques. Afterwards, two case studies for multiple-input-multiple- output (MIMO) communications, including DL-based channel state information feedback and signal detection, are presented to show the feasibility and potential of these …