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Automated guided vehicles (AGVs), are the state-of-the-art, and are often used to facilitate automatic storage and retrieval systems (AS/RS). In this paper, we focus on the dispatching of AGVs in a flexible manufacturing system (FMS). A FMS environment requires a flexible and adaptable material handling system. We model an AGV system by using network structure. This network model of an AGV dispatching has simplexes decision variables with considering most AGV problem’s constraints, for example capacity of AGVs, precedence constraints among the processes, deadlock control. Furthermore, these problems can be solved by using a lot of heuristic algorithms as network optimization problems. We are also proposed an effective evolutionary approach for solving a kind of AGV’s problems in which minimizing time required to complete all jobs (i.e. makespan) and minimizing the number of AGVs …