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In the increasingly interconnected world, the relationship among learning and teaching, innovation and innovativeness, entrepreneurship, business development, as well as sustainable and inclusive socio-economic growth and development, requires a multidimensional interdisciplinary analysis. Importantly, information systems and advancements in sophisticated information and communication technologies (ICTs) are consequential for the potential inherent in education to be exploited. This edited volume opens discussion on ways and strategies of exploiting opportunities and synergies, which the maturing relationship between smart education and information systems offers. In this context, the objective of this chapter is to suggest how to (re) define smart education and how to reap its benefits in view of promoting dynamic education and information systems conducive to the emergence of innovation networks in …