作者
Martin Diers, Caroline Koeppe, Pinar Yilmaz, Kati Thieme, Jaana Markela-Lerenc, Marcus Schiltenwolf, Klaus van Ackern, Herta Flor
发表日期
2008/6/1
期刊
Journal of Clinical Neurophysiology
卷号
25
期号
3
页码范围
153-160
出版商
LWW
简介
To determine the presence of perceptual sensitization and related brain responses we examined 15 patients with fibromyalgia syndrome and 15 healthy controls comparable in age and sex. Multichannel EEG recordings and pain ratings were obtained during the presentation of 800 painful electrical intramuscular and intracutaneous stimuli to the left m. erector spinae and the left m. extensor digitorum. The stimulus intensity was adjusted to 50% between pain threshold and tolerance. Detection and pain thresholds were significantly lower in the fibromyalgia syndrome group. Sensitization occurred for both groups during intramuscular stimulation. In the EEG data the fibromyalgia syndrome patients showed higher N80 amplitudes compared with the healthy controls. Arm stimulation and intramuscular stimulation yielded higher N80 and N150 amplitudes compared with intracutaneous stimulation or stimulation of the …
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M Diers, C Koeppe, P Yilmaz, K Thieme… - Journal of Clinical Neurophysiology, 2008