作者
BJ Casey, Jeffery N Epstein, Jason Buhle, Conor Liston, Matthew C Davidson, Simon T Tonev, Julie Spicer, Sumit Niogi, Alexander J Millner, Allan Reiss, Amy Garrett, Stephen P Hinshaw, Laurence L Greenhill, Keith M Shafritz, Alan Vitolo, Lisa A Kotler, Matthew A Jarrett, Gary Glover
发表日期
2007/11
期刊
American Journal of psychiatry
卷号
164
期号
11
页码范围
1729-1736
出版商
American Psychiatric Association
简介
Objective
Many studies have linked the structure and function of frontostriatal circuitry to cognitive control deficits in attention deficit hyperactivity disorder (ADHD). Few studies have examined the role of white matter tracts between these structures or the extent to which white matter tract myelination and regularity correlate in family members with the disorder. Method
Functional imaging maps from a go/nogo task were used to identify portions of the ventral prefrontal cortex and striatum involved in suppressing an inappropriate action (i.e., cognitive control) in 30 parent-child dyads (N=60), including 20 dyads (N=40) with ADHD and 10 dyads (N=20) without ADHD. An automated fiber-tracking algorithm was used to delineate white matter fibers adjacent to these functionally defined regions based on diffusion tensor images. Fractional anisotropy, an index of white matter tract myelination and …引用总数
学术搜索中的文章
BJ Casey, JN Epstein, J Buhle, C Liston, MC Davidson… - American Journal of psychiatry, 2007