作者
Lilian Maria Sobreira Tanaka, Luciano Cesar Pontes Azevedo, Marcelo Park, Guilherme Schettino, Antonio Paulo Nassar Jr, Alvaro Réa-Neto, Luana Tannous, Vicente Ces de Souza-Dantas, André Torelly, Thiago Lisboa, Claudio Piras, Frederico Bruzzi Carvalho, Marcelo de Oliveira Maia, Fabio Poianas Giannini, Flavia Ribeiro Machado, Felipe Dal-Pizzol, Alexandre Guilherme Ribeiro de Carvalho, Ronaldo Batista dos Santos, Paulo Fernando Guimarães Morando Marzocchi Tierno, Marcio Soares, Jorge Ibrain Figueira Salluh, ERICC study investigators
发表日期
2014/8/1
期刊
Critical Care
卷号
18
期号
4
页码范围
1-10
出版商
BioMed Central
简介
Introduction
Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, the association of early oversedation with clinical outcomes has not been thoroughly evaluated. The aim of this study was to assess the association of early sedation strategies with outcomes of critically ill adult patients under mechanical ventilation (MV).
Methods
A secondary analysis of a multicenter prospective cohort conducted in 45 Brazilian ICUs, including adult patients requiring ventilatory support and sedation in the first 48 hours of ICU admissions, was performed. Sedation depth was evaluated after 48 hours of MV. Multivariate analysis was used to identify variables associated with hospital mortality.
Results
A total of 322 patients were evaluated. Overall, ICU and hospital …
学术搜索中的文章
LMS Tanaka, LCP Azevedo, M Park, G Schettino… - Critical care, 2014