作者
Eszter Panna Vamos, Matthew Harris, Christopher Millett, Utz J Pape, Kamlesh Khunti, Vasa Curcin, Mariam Molokhia, Azeem Majeed
发表日期
2012/8/30
期刊
Bmj
卷号
345
出版商
British Medical Journal Publishing Group
简介
Objective To examine the effect of systolic and diastolic blood pressure achieved in the first year of treatment on all cause mortality in patients newly diagnosed with type 2 diabetes, with and without established cardiovascular disease.
Design Retrospective cohort study.
Setting United Kingdom General Practice Research Database, between 1990 and 2005.
Participants 126 092 adult patients (age ≥18 years) with a new diagnosis of type 2 diabetes who had been registered with participating practices for at least 12 months.
Main outcome measure All cause mortality.
Results Before diagnosis, 12 379 (9.8%) patients had established cardiovascular disease (myocardial infarction or stroke). During a median follow-up of 3.5 years, we recorded 25 495 (20.2%) deaths. In people with cardiovascular disease, tight control of systolic (<130 mm Hg) and diastolic (<80 mm Hg) blood pressure was not associated with …
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