作者
Bianca de Almeida-Pititto, Fernando Flexa Ribeiro-Filho, Marcio Sommer Bittencourt, Paulo A Lotufo, Isabela Bensenor, Sandra RG Ferreira
发表日期
2016/12
期刊
Diabetology & metabolic syndrome
卷号
8
页码范围
1-7
出版商
BioMed Central
简介
Background
This cross-sectional analysis evaluated whether determination of E-selectin concentrations could identify deterioration of cardiometabolic risk profile or subclinical atherosclerosis in individuals at low-to-moderate risk included in The Brazilian Longitudinal Study of Adult Health—ELSA-Brasil.
Methods
A sample of 984 individuals from ELSA-Brasil (35–54 years) without cardiovascular disease or diabetes was stratified according to E-selectin tertiles. Traditional risk factors, inflammatory markers and categories of coronary artery calcium (CAC) scores were evaluated across the tertiles by ANOVA or Chi-squared test. In linear regression models, associations of E-selectin levels with insulin resistance index, adjusted for age, sex and adiposity were tested.
Results
The mean age of the participants was 45.8 (SD 4 …
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B de Almeida-Pititto, FF Ribeiro-Filho, MS Bittencourt… - Diabetology & metabolic syndrome, 2016