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In this article, a Hybrid strain-hardening Model for slip driven plasticity is introduced. The model distinguishes between the contributions of glissile and stored dislocations, and polar and non-polar dislocations. The core idea relies on a two step-approach in which all glissile non-polar dislocations on given slip systems are represented by a virtual dislocation loop which evolution is modeled by a dislocation dynamics approach, while transformations of dislocations from glissile to stored, resulting from short-range dislocation–dislocation interactions, are based on phenomenological relations informed by dislocation dynamics simulations on dislocation pair interactions. The constitutive model developed should then allow for a reduction in fitting parameters and should be suitable to predict complex loading. Besides, the Hybrid Model is able to predict dislocation densities for all kinds of populations, including junctions …