作者
Athina Tzovara, Sofie S Meyer, James J Bonaiuto, Aslan Abivardi, Raymond J Dolan, Gareth R Barnes, Dominik R Bach
发表日期
2019/10/1
期刊
Human brain mapping
卷号
40
期号
14
页码范围
4114-4129
出版商
John Wiley & Sons, Inc.
简介
Learning to associate neutral with aversive events in rodents is thought to depend on hippocampal and amygdala oscillations. In humans, oscillations underlying aversive learning are not well characterised, largely due to the technical difficulty of recording from these two structures. Here, we used high‐precision magnetoencephalography (MEG) during human discriminant delay threat conditioning. We constructed generative anatomical models relating neural activity with recorded magnetic fields at the single‐participant level, including the neocortex with or without the possibility of sources originating in the hippocampal and amygdalar structures. Models including neural activity in amygdala and hippocampus explained MEG data during threat conditioning better than exclusively neocortical models. We found that in both amygdala and hippocampus, theta oscillations during anticipation of an aversive event had …
学术搜索中的文章
A Tzovara, SS Meyer, JJ Bonaiuto, A Abivardi… - Human brain mapping, 2019