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Methods:

Data were derived from a prospective database of newly diagnosed children with inflammatory bowel disease established in 2002 at 18 pediatric gastroenterology centers in the United States and Canada. At diagnosis, at 30 days and 3 months after diagnosis, and quarterly thereafter, children (< 16 years of age) with Crohn disease had disease assessment performed by PGA and PCDAI. Disease management was provided according to the dictates of the attending gastroenterologist and not by predetermined protocol.

Results:

181 patients had concomitant PGA and PCDAI performed at diagnosis, and 95 of these had similar assessment at short-term follow up. Mean±SD PCDAI scores for mild, moderate, and severe disease by PGA at diagnosis were 19.5±10.4, 32.2±12.7, and 47.8±14.9, respectively (P< 0.001 for all comparisons). Mean±SD PCDAI for inactive disease after treatment was 5.2±5.4. Receiver …