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Coupling Software Defined Networking (SDN) and Network Function virtualization (NFV) has proved to be a promising paradigm for flexible resource provisioning in future networks. Network slicing is a very recent methodology that can be used in this paradigm for accommodating new services with wide different requirements over the same physical network. In this work, we propose a mathematical formulation of an optimization problem for an end-to-end (E2E) network slices deployment for different 5G-based use-cases. Each use case such as video streaming, intelligent transport, e-Health and public safety, has its own availability, reliability and delay tolerance requirements. Then, in view of the fact that the optimization problem is NP-Hard, a low-cost and efficient heuristic algorithm has been proposed. Last, the efficiency of the proposed algorithm is validated through extensive simulation. Applying our algorithm …