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A 5G network communicates per-slice constraints for QoS parameter values from a centralized unit (CU) to a MAC scheduler of a distributed unit (DU). The CU communicates these per-slice constraints, rather than or in addition to per-DRB constraints, to the MAC scheduler over the CU/DU interface. In some implementations, the CU/DU interface is an F1 air interface as defined in specification 38.473 in the 3GPP standard. In some implementations, the DU provides per-slice performance feedback over the CU/DU interface. Based on such feedback, the CU may adjust the per-slice QoS constraints.