作者
Claudio Romano, Valeria Ferrau', Francesca Cavataio, Giuseppe Iacono, Massimo Spina, Elena Lionetti, Fabrizio Comisi, Annalisa Famiani, Donatella Comito
发表日期
2014/10
期刊
Journal of paediatrics and child health
卷号
50
期号
10
页码范围
E68-E71
出版商
Blackwell Publishing Asia
简介
Aim:  Functional abdominal pain (FAP) is a frequent condition affecting 10–20% of children and can be considered within the classification of functional gastrointestinal disorders (FGID). The objective of this study was to determine the effect of daily supplementation with the probiotic Lactobacillus reuteri DSM 17938 in children with FAP.
Methods:  The children (aged 6–16 years) were screened for FAP as defined in the Rome III criteria and 60 patients were recruited in this double‐blind, randomised, placebo‐controlled trial. The children were randomly allocated to receive either L. reuteri (2 × 108 CFU/day) or identical placebo for 4 weeks followed by a 4‐week follow‐up period without supplementation. Frequency and intensity of pain was self‐recorded by the subjects.
Results:  The L. reuteri‐supplemented children had significantly lower pain intensity compared with the placebo controls.
Conclusions …
引用总数
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学术搜索中的文章
C Romano, V Ferrau', F Cavataio, G Iacono, M Spina… - Journal of paediatrics and child health, 2014