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Forensic Dentistry or Odontology is the application of dental science to legal investigations where other evidences are not easily accessible. These cases include mass disasters, homicides, sexual assault, violent crimes, child abuse cases, self-inflicted bite marks, etc. Forensic odontologists use the dentistry skills in personal identification through examination and comparison of dental evidence such as bite marks found in a crime scene or identification of human residues centered on dental registers. Bite marks are considered as an important alternate to fingerprinting and DNA analysis in forensic investigations. It aids in identifying the manner of crime based on the site of the mark. Dental impression can be created to represent the full structure of teeth helping the forensic odontologist to match the teeth of the suspect with the bite mark. The aim of the present review was to highlight the significance of dentistry in forensic investigations by discussing emerging approaches used in dentistry for medico-legal practice. The importance of bite-mark analysis as well as the role of teeth in estimating the age, gender and race of individuals in cases where evidence associated with the victims are not accessible such as mass disasters were discussed. This review can provide better understanding of methodologies used in forensic science when investigating cases dealing with teeth or dental remains.