作者
Hesham A Abowali, Matteo Paganini, Garrett Enten, Ayman Elbadawi, Enrico M Camporesi
发表日期
2021/4/1
来源
Journal of Cardiothoracic and Vascular Anesthesia
卷号
35
期号
4
页码范围
1134-1142
出版商
WB Saunders
简介
Objective
To evaluate reports from the published literature of all randomized clinical trials (RCT) comparing postoperative sedation with dexmedetomidine versus propofol in adult patients, after open cardiac surgery.
Design
A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research and Quality databases was completed through June 2020. Meta-analysis of all published RCT comparing dexmedetomidine versus propofol utilization in the postoperative phase, using the standard Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist.
Setting
Assemblage and critical discussion of 11 RCTs comparing postoperative sedation from standard published reports from 2003 to 2019.
Participants
The study comprised 1,184 patients and analyzed critical discussion of time-based parameters (time to extubation, intensive care unit length of stay, and hospital length of …
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HA Abowali, M Paganini, G Enten, A Elbadawi… - Journal of Cardiothoracic and Vascular Anesthesia, 2021