作者
Guillaume Voiriot, Benoit Visseaux, Johana Cohen, Liem Binh Luong Nguyen, Mathilde Neuville, Caroline Morbieu, Charles Burdet, Aguila Radjou, François-Xavier Lescure, Roland Smonig, Laurence Armand-Lefèvre, Bruno Mourvillier, Yazdan Yazdanpanah, Jean-Francois Soubirou, Stephane Ruckly, Nadhira Houhou-Fidouh, Jean-François Timsit
发表日期
2016/12
期刊
Critical Care
卷号
20
页码范围
1-9
出版商
BioMed Central
简介
Background
Multiplex polymerase chain reaction (mPCR) enables recovery of viruses from airways of patients with community-acquired pneumonia (CAP), although their clinical impact remains uncertain.
Methods
Among consecutive adult patients who had undergone a mPCR within 72 hours following their admission to one intensive care unit (ICU), we retrospectively included those with a final diagnosis of CAP. Four etiology groups were clustered: bacterial, viral, mixed (viral-bacterial) and no etiology. A composite criterion of complicated course (hospital death or mechanical ventilation > 7 days) was used. A subgroup analysis compared patients with bacterial and viral-bacterial CAP matched on the bacterial pathogens.
Results
Among 174 patients (132 men [76 %], age 63 [53–75] years, SAPSII 38 [27;55], median …
学术搜索中的文章
G Voiriot, B Visseaux, J Cohen, LBL Nguyen… - Critical Care, 2016