作者
Quentin Le Hingrat, Benoit Visseaux, Cédric Laouenan, Sarah Tubiana, Lila Bouadma, Yazdan Yazdanpanah, Xavier Duval, Charles Burdet, Houria Ichou, Florence Damond, Mélanie Bertine, Nabil Benmalek, Christophe Choquet, Jean-François Timsit, Jade Ghosn, Charlotte Charpentier, Diane Descamps, Nadhira Houhou-Fidouh, Alpha Diallo, Soizic Le Mestre, Noémie Mercier, Christelle Paul, Ventzislava Petrov-Sanchez, Denis Malvy, Catherine Chirouze, Claire Andrejak, François Dubos, Patrick Rossignol, Olivier Picone, François Bompart, Tristan Gigante, Morgane Gilg, Bénédicte Rossignol, Claire Levy-Marchal, Marine Beluze, Jean Sébastien Hulot, Delphine Bachelet, Krishna Bhavsar, Anissa Chair, Camille Couffignal, Charlene Da Silveira, Marie Pierre Debray, Philippine Eloy, Marina Esposito-Farese, Nadia Ettalhaoui, Nathalie Gault, Isabelle Gorenne, Isabelle Hoffmann, Ouifiya Kafif, Sabrina Kali, Antoine Khalil, Cédric Laouénan, Samira Laribi, Minh Le, François-Xavier Lescure, Jean Christophe Lucet, France Mentré, Jimmy Mullaert, Nathan Peiffer-Smadja, Gilles Peytavin, Carine Roy, Marion Schneider, Nassima Si Mohammed, Lysa Tagherset, Coralie Tardivon, Marie Capucine Tellier, Théo Trioux, Noémie Vanel, Romain Basmaci, François Angoulvant, Florentia Kaguelidou, Justine Pages, Christelle Tual, Aurélie Veislinger, Sandrine Couffin-Cardiergues, Hélène Esperou, Ikram Houas, Salma Jaafoura, Aurélie Papadopoulos, Alexandra Coelho, Alphonsine Diouf, Alexandre Hoctin, Marina Mambert, Maude Bouscambert, Alexandre Gaymard, Bruno Lina, Manuel Rosa-Calatrava, Olivier Terrier, Dehbia Benkerrou, Céline Dorival, Amina Meziane, François Téoulé, Jérémie Guedj, Hervé Le Nagard, Guillaume Lingas, Nadège Neant, Laurent Abel, Mathilde Desvallée, Coralie Khan, Dominique Deplanque, Sylvie Behilill, Vincent Enouf, Hugo Mouquet, Sylvie Van Der Werf, Minerva Cervantes-Gonzalez, Eric D'ortenzio, Oriane Puéchal, Caroline Semaille, Marion Noret, Manuel Etienne, Yves Levy, Aurélie Wiedemann, Fanny Abad, Dominique Abry, Loubna Alavoine, Jean-Sébastien Allain, Karline Amiel-Taieb, Pierre Audoin, Shana Augustin, Sandrine Ayala, Hélène Bansard, Fréderique Bertholon, Nolwenn Boissel, Elisabeth Botelho-Nevers, Kévin Bouiller, Marilou Bourgeon, Mathilde Boutrou, Lysiane Brick, Léa Bruneau, Eric Caumes, Agnès Chabouis, Eric Chan Thien, Bruno Coignard, Yolande Costa, Virginie Costenoble, Sylvie Cour, Claire Cracowski, Jean-Luc Cracowski, Stéphane Dequand, Mireille Desille-Dugast, Maxime Desmarets, Maelle Detoc, Marie Dewitte, Felix Djossou, Jean-Luc Ecobichon, Elise Elrezzi, William Faurous, Viviane Fortuna, Julie Fouchard, Emilie Gantier
发表日期
2021/5/1
期刊
Clinical Microbiology and Infection
卷号
27
期号
5
页码范围
789. e1-789. e5
出版商
Elsevier
简介
Objectives
Molecular assays on nasopharyngeal swabs remain the cornerstone of COVID-19 diagnostics. The high technicalities of nasopharyngeal sampling and molecular assays, as well as scarce resources of reagents, limit our testing capabilities. Several strategies failed, to date, to fully alleviate this testing process (e.g. saliva sampling or antigen testing on nasopharyngeal samples). We assessed the clinical performances of SARS-CoV-2 nucleocapsid antigen (N-antigen) ELISA detection in serum or plasma using the COVID-19 Quantigene® (AAZ, France) assay.
Methods
Performances were determined on 63 serum samples from 63 non-COVID patients and 227 serum samples (165 patients) from the French COVID and CoV-CONTACT cohorts with RT-PCR-confirmed SARS-CoV-2 infection, including 142 serum samples (114 patients) obtained within 14 days after symptom onset.
Results
Specificity was 98.4 …
引用总数