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Binary classifiers have typically been the norm for building classification models in the Machine Learning community. However, an alternate to binary classification is one-class classification, which aims to build models using only a single class of data. This is particularly useful when there is an over-abundance of data of a particular class. In such imbalanced cases, binary classifiers may not perform very well, and one-class classifiers then become the viable option. In this paper, we are interested in investigating the performance of binary and one-class classifiers as the level of imbalance increases, and, thus, uncertainty in the second class. Our objective is to gain insight into which classification paradigm becomes more suitable as imbalance and uncertainty increase. To this end, we conduct experiments on various datasets, both artificial and from the UCI repository, and monitor the performance of the binary and …