作者
Rezvan Hosseinzadeh, Mohammad Barary, Hamed Mehdinezhad, Terence T Sio, Florian Langer, Sahar Khosravi
发表日期
2022/5
期刊
Research and Practice in Thrombosis and Haemostasis
卷号
6
期号
4
页码范围
e12750
简介
Background
Severe side effects after vaccination with coronavirus disease 2019 (COVID‐19) vaccines are rare but can be fatal. To date, vaccine‐induced immune thrombotic thrombocytopenia (VITT) cases have been reported after injection of mRNA and adenoviral vectors COVID‐19 vaccines. Here, we report the second suspected case of VITT after vaccination with the Sinopharm vaccine, an inactive vaccine.
Key Clinical Question
The Key Clinical Question was to determine whether inactivated COVID‐19 vaccines could induce VITT and how to diagnose and treat such cases.
Clinical Approach and Conclusions
Our patient developed deteriorating symptoms the day after vaccination and was admitted to the emergency department on day 5 after vaccination. After performing laboratory analysis, thrombosis with thrombocytopenia was suggested, further confirmed by highly positive anti‐heparin–platelet factor 4 …
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R Hosseinzadeh, M Barary, H Mehdinezhad, TT Sio… - Research and Practice in Thrombosis and …, 2022