作者
Peter Yarsky
发表日期
2020/7/16
期刊
Journal of Global Health Reports
卷号
4
页码范围
e2020059
出版商
International Society of Global Health
简介
# Background The objective of the current work was to develop a simple predictive model of the spread of the novel coronavirus (i.e., 2019-nCoV or SARS-CoV-2) in the United States. The intent was to develop a simple, fast running model that could be used to make predictions regarding the effectiveness of various public policy proposals to mitigate or contain the spread of the virus. In the US, various states have adopted a patchwork of different strategies to manage the novel coronavirus disease (COVID-19) outbreak. The model can be used to predict medical resource needs to support comparison of possible strategies and forecast consequences in terms of virus-caused casualties. # Methods The simple model was constructed based on the SIR (Susceptible, Infected, Removed) epidemiological model. The current work builds on the work of Tang, et al., to enhance the SIR model with additional subpopulations. Accounting for different subpopulations in the model requires the use of additional differential equations to track the evolution of the subpopulations, but the basic principle is the same. The method tracks subpopulations of individuals that are exposed (but not yet showing symptoms) (E), asymptomatic carriers (A), and quarantined individuals (if quarantine measures are adopted as part of mitigation or containment strategies) (Q). The current model throughout this paper is referred to as the SEIR+AQ model. # Results Several SEIR+AQ models were constructed for different states in the US. In these different models, the only factors adjusted are specific to the state (e.g., population) and a small number of “cultural” parameters. The …
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