作者
Naveed Ahmed, Zeshan Ali, Mahpara Riaz, Basit Zeshan, Javed Iqbal Wattoo, Muhammad Naveed Aslam
发表日期
2020/5
期刊
Asian Pacific journal of cancer prevention: APJCP
卷号
21
期号
5
页码范围
1333
出版商
Shahid Beheshti University of Medical Sciences
简介
Objectives:
The objectives of this study were to evaluate P. Aeruginosa isolates from cancer patients for the phenotypic pattern of antibiotic resistance and to detect the gene responsible for virulence as well as antibiotic resistance.
Methods:
A total of 227 P. aeruginosa isolates were studied and 11 antibiotics were applied for susceptibility testing. PCR detection of the genes BIC, TEM, IMP, SPM, AIM, KPC, NDM, GIM, VIM, OXA, toxA and oprI was done. Finally, the carbapenem resistant isolates were tested for phenotypic identification of carbapenemase enzyme by Modified Hodge test.
Results:
The results showed that the isolates were resistant to imipenem (95%), cefipime (93%), meropenem (90%), polymixin B (71%), gentamicin (65%), ciprofloxacin (48%), ceftazidime (40%), levofloxacin (39%), amikacin (32%), tobramycin (28%) and tazobactum (24%). The PCR detection of the carbapenem resistant genes showed …
学术搜索中的文章
N Ahmed, Z Ali, M Riaz, B Zeshan, JI Wattoo… - Asian Pacific journal of cancer prevention: APJCP, 2020