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Peroni DG, Pescollderungg L, Piacentini GL, Rigotti E, Maselli M, Watschinger K, Piazza M, Pigozzi R, Boner AL. Immune regulatory cytokines in the milk of lactating women from farming and urban environments.
Pediatr Allergy Immunol 2010: 21: 977–982.
© 2010 John Wiley & Sons A/S

Children living on farms have fewer allergies. It is unclear whether breastfeeding in different environments contributes to preventing allergies by exposing offspring to different cytokines that can modulate immune responses. The aim of this study was to quantify and compare levels of Transforming Growth Factor‐β1 (TGF‐β1) and Interleukin‐10 (IL‐10) in the colostrum and mature milk of mothers living in towns at sea level (references) and mothers on farms. Milk samples were collected within 3 days postpartum (colostrum) and at the first month of the baby’s life (mature milk). Sixty‐nine reference mothers and 45 farm mothers …