作者
Osamu Ohno, Taeko Watabe, Kazuhiko Nakamura, Masaru Kawagoshi, Nobuo Uotsu, Tomohiro Chiba, Masayoshi Yamada, Kohji Yamaguchi, Kaoru Yamada, Kenji Miyamoto, Daisuke Uemura
发表日期
2010/7/23
期刊
Bioscience, biotechnology, and biochemistry
卷号
74
期号
7
页码范围
1504-1506
出版商
Oxford University Press
简介
An EtOH extract of fruits of Piper longum was found to exhibit a potent inhibitory effect against α-melanocyte-stimulating hormone (α-MSH)-induced melanin production in B16 mouse melanoma cells. Bioassay-directed fractionation led to the isolation of prenylated phenolic compounds bakuchiol, bavachin, and isobavachalcone. These compounds and the crude extract of the fruits of P. longum may have suppressive effects against pigmentation by melanin in the skin.
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O Ohno, T Watabe, K Nakamura, M Kawagoshi… - Bioscience, biotechnology, and biochemistry, 2010